Productive life cycle of adeno-associated virus serotype 2 in the complete absence of a conventional polyadenylation signal

We showed that WT adeno-associated virus serotype 2 (AAV2) genome devoid of a conventional polyadenylation [poly(A)] signal underwent complete genome replication, encapsidation and progeny virion production in the presence of adenovirus. The infectivity of the progeny virion was also retained. Using...

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Bibliografiske detaljer
Udgivet i:J Gen Virol
Main Authors: Wang, Lina, Yin, Zifei, Wang, Yuan, Lu, Yuan, Zhang, Daniel, Srivastava, Arun, Ling, Changquan, Aslanidi, George V., Ling, Chen
Format: Artigo
Sprog:Inglês
Udgivet: Society for General Microbiology 2015
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635500/
https://ncbi.nlm.nih.gov/pubmed/26297494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000229
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