(Z)3,4,5,4′-trans-tetramethoxystilbene, a new analogue of resveratrol, inhibits gefitinb-resistant non-small cell lung cancer via selectively elevating intracellular calcium level

Calcium is a second messenger which is required for regulation of many cellular processes. However, excessive elevation or prolonged activation of calcium signaling would lead to cell death. As such, selectively regulating calcium signaling could be an alternative approach for anti-cancer therapy. R...

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Publicado en:Sci Rep
Autores principales: Fan, Xing-Xing, Yao, Xiao-Jun, Xu, Su Wei, Wong, Vincent Kam-Wai, He, Jian-Xing, Ding, Jian, Xue, Wei-Wei, Mujtaba, Tahira, Michelangeli, Francesco, Huang, Min, Huang, Jun, Xiao, Da-Kai, Jiang, Ze-Bo, Zhou, Yan-Ling, Kin-Ting Kam, Richard, Liu, Liang, Lai-Han Leung, Elaine
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635386/
https://ncbi.nlm.nih.gov/pubmed/26542098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16348
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