3′-hydroxy-3,4,5,4′-tetramethoxystilbene, the metabolite of resveratrol analogue DMU-212, inhibits ovarian cancer cell growth in vitro and in a mice xenograft model

In screening studies, the cytotoxic activity of four metabolites of resveratrol analogue 3,4,5,4′-tetramethoxystilbene (DMU-212) against A-2780 and SKOV-3 ovarian cancer cells was investigated. The most active metabolite, 3′-hydroxy-3,4,5,4′-tetramethoxystilbene (DMU-214), was chosen for further stu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Piotrowska-Kempisty, Hanna, Ruciński, Marcin, Borys, Sylwia, Kucińska, Małgorzata, Kaczmarek, Mariusz, Zawierucha, Piotr, Wierzchowski, Marcin, Łażewski, Dawid, Murias, Marek, Jodynis-Liebert, Jadwiga
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009320/
https://ncbi.nlm.nih.gov/pubmed/27585955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32627
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