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Protein aggregates are associated with replicative aging without compromising protein quality control

Differentiation of cellular lineages is facilitated by asymmetric segregation of fate determinants between dividing cells. In budding yeast, various aging factors segregate to the aging (mother)-lineage, with poorly understood consequences. In this study, we show that yeast mother cells form a prote...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Saarikangas, Juha, Barral, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635334/
https://ncbi.nlm.nih.gov/pubmed/26544680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06197
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