Gelsemine alleviates both neuropathic pain and sleep disturbance in partial sciatic nerve ligation mice

AIM: Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans (Gardn & Champ) Benth., is effective in mitigating chronic pain in rats. In the present study we investigated whether the alkaloid improved sleep disturbance, the most common comorbid symptoms of chronic pain, in a mouse model o...

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Vydáno v:Acta Pharmacol Sin
Hlavní autoři: Wu, Yu-er, Li, Ya-dong, Luo, Yan-jia, Wang, Tian-xiao, Wang, Hui-jing, Chen, Shuo-nan, Qu, Wei-min, Huang, Zhi-li
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635333/
https://ncbi.nlm.nih.gov/pubmed/26388157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.86
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