Neuropathic Pain in Rats with a Partial Sciatic Nerve Ligation Is Alleviated by Intravenous Injection of Monoclonal Antibody to High Mobility Group Box-1

High mobility group box-1 (HMGB1) is associated with the pathogenesis of inflammatory diseases. A previous study reported that intravenous injection of anti-HMGB1 monoclonal antibody significantly attenuated brain edema in a rat model of stroke, possibly by attenuating glial activation. Peripheral n...

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Bibliographic Details
Main Authors: Nakamura, Yoki, Morioka, Norimitsu, Abe, Hiromi, Zhang, Fang Fang, Hisaoka-Nakashima, Kazue, Liu, Keyue, Nishibori, Masahiro, Nakata, Yoshihiro
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749159/
https://ncbi.nlm.nih.gov/pubmed/23991202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073640
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