Prednisone treatment inhibits the differentiation of B lymphocytes into plasma cells in MRL/MpSlac-lpr mice

AIM: A number of evidence shows that the differentiation of B lymphocytes into plasma cells plays an important role in lupus pathogenesis. In this study we investigated how prednisone, a classical therapeutic drug for autoimmune diseases, regulated plasma cell differentiation in MRL/MpSlac-lpr mice....

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Bibliographic Details
Published in:Acta Pharmacol Sin
Main Authors: Yan, Shang-xue, Deng, Xiao-mei, Wang, Qing-tong, Sun, Xiao-jing, Wei, Wei
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635331/
https://ncbi.nlm.nih.gov/pubmed/26456588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.76
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