Effects of long-term smoking on the activity and mRNA expression of CYP isozymes in rats

BACKGROUND: To investigate the effect of long-term smoking on the activity and mRNA expression of cytochrome P450 (CYP) enzymes. METHODS: Sprague-Dawley rats were exposed to passive smoking 6 cigarettes per day for 180 days. A cocktail solution which contained phenacetin (20 mg/kg), tolbutamide (5 m...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Thorac Dis
Main Authors: He, Xiao-Meng, Zhou, Ying, Xu, Ming-Zhen, Li, Yang, Li, Hu-Qun, Li, Wei-Yong
Format: Artigo
Jezik:Inglês
Izdano: AME Publishing Company 2015
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635270/
https://ncbi.nlm.nih.gov/pubmed/26623094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2072-1439.2015.10.07
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