Cathepsin L acutely alters microvessel integrity within the neurovascular unit during focal cerebral ischemia

During focal cerebral ischemia, the degradation of microvessel basal lamina matrix occurs acutely and is associated with edema formation and microhemorrhage. These events have been attributed to matrix metalloproteinases (MMPs). However, both known protease generation and ligand specificities sugges...

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Bibliografiska uppgifter
I publikationen:J Cereb Blood Flow Metab
Huvudupphovsmän: Gu, Yu-Huan, Kanazawa, Masato, Hung, Stephanie Y, Wang, Xiaoyun, Fukuda, Shunichi, Koziol, James A, del Zoppo, Gregory J
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635247/
https://ncbi.nlm.nih.gov/pubmed/26198177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.170
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