20-Hydroxyeicosatetraenoic Acid Inhibition by HET0016 Offers Neuroprotection, Decreases Edema, and Increases Cortical Cerebral Blood Flow in a Pediatric Asphyxial Cardiac Arrest Model in Rats

Vasoconstrictive and vasodilatory eicosanoids generated after cardiac arrest (CA) may contribute to cerebral vasomotor disturbances and neurodegeneration. We evaluated the balance of vasodilator/vasoconstrictor eicosanoids produced by cytochrome P450 (CYP) metabolism, and determined their role on co...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Cereb Blood Flow Metab
Autori principali: Shaik, Jafar Sadik B, Poloyac, Samuel M, Kochanek, Patrick M, Alexander, Henry, Tudorascu, Dana L, Clark, Robert SB, Manole, Mioara D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
Soggetti:
Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635230/
https://ncbi.nlm.nih.gov/pubmed/26058691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.117
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi