Compartment-dependent mitochondrial alterations in experimental ALS, the effects of mitophagy and mitochondriogenesis

Amyotrophic lateral sclerosis (ALS) is characterized by massive loss of motor neurons. Data from ALS patients and experimental models indicate that mitochondria are severely damaged within dying or spared motor neurons. Nonetheless, recent data indicate that mitochondrial preservation, although prev...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Natale, Gianfranco, Lenzi, Paola, Lazzeri, Gloria, Falleni, Alessandra, Biagioni, Francesca, Ryskalin, Larisa, Fornai, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635226/
https://ncbi.nlm.nih.gov/pubmed/26594150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00434
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