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Ultrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesis

The key role of mitochondria in patients affected by amyotrophic lateral sclerosis (ALS) is well documented by electron microscopy studies of motor neurons within spinal cord and brainstem. Nonetheless, recent studies challenged the role of mitochondria placed within the cell body of motor neuron. I...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Ruffoli, Riccardo, Bartalucci, Alessia, Frati, Alessandro, Fornai, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555074/
https://ncbi.nlm.nih.gov/pubmed/26388731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00341
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