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Identification of structural alerts for liver and kidney toxicity using repeated dose toxicity data
BACKGROUND: The potential for a compound to cause hepatotoxicity and nephrotoxicity is a matter of extreme interest for human health risk assessment. To assess liver and kidney toxicity, repeated-dose toxicity (RDT) studies are conducted mainly on rodents. However, these tests are expensive, time-co...
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| Publicado no: | Chem Cent J |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4635184/ https://ncbi.nlm.nih.gov/pubmed/26550029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-015-0139-7 |
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