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Ribavirin contributes to eradicate hepatitis C virus through polarization of T helper 1/2 cell balance into T helper 1 dominance

The mechanism of action of ribavirin (RBV) as an immunomodulatory and antiviral agent and its clinical significance in the future treatment of patients with hepatitis C virus (HCV) infection are reviewed. RBV up-regulates type 1 and/or 2 cytokines to modulate the T helper (Th) 1/2 cell balance to Th...

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Bibliografske podrobnosti
izdano v:World J Hepatol
Main Authors: Nakatsuka, Katsuhisa, Atsukawa, Masanori, Shimizu, Masumi, Takahashi, Hidemi, Kawamoto, Chiaki
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Inc 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635144/
https://ncbi.nlm.nih.gov/pubmed/26557951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v7.i25.2590
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