Integrated, step-wise, mass-isotopomeric flux analysis of the TCA Cycle

Mass isotopomer multi-ordinate spectral analysis (MIMOSA) is a step-wise flux analysis platform to measure discrete glycolytic and mitochondrial metabolic rates. Importantly, direct citrate synthesis rates were obtained by deconvolving the mass spectra generated from [U-(13)C(6)]-D-glucose labeling...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Alves, Tiago C., Pongratz, Rebecca L., Zhao, Xiaojian, Yarborough, Orlando, Sereda, Sam, Shirihai, Orian, Cline, Gary W., Mason, Graeme, Kibbey, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635072/
https://ncbi.nlm.nih.gov/pubmed/26411341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.08.021
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