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Ribosome structure reveals preservation of active sites in the presence of a P-site wobble mismatch

Translation initiation in the P site occasionally occurs at atypical (non-AUG) start codons, including those forming a mismatch in the third (wobble) position. During elongation, however, a pyrimidine-pyrimidine wobble mismatch may trigger a translation quality control mechanism, whereby the P-site...

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Bibliografiska uppgifter
I publikationen:Structure
Huvudupphovsmän: Svidritskiy, Egor, Korostelev, Andrei A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635039/
https://ncbi.nlm.nih.gov/pubmed/26412335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.08.011
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