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Multiple Origins of Mutations in the mdr1 Gene—A Putative Marker of Chloroquine Resistance in P. vivax

BACKGROUND: Chloroquine combined with primaquine has been the recommended antimalarial treatment of Plasmodium vivax malaria infections for six decades but the efficacy of this treatment regimen is threatened by chloroquine resistance (CQR). Single nucleotide polymorphisms (SNPs) in the multidrug re...

詳細記述

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書誌詳細
出版年:PLoS Negl Trop Dis
主要な著者: Schousboe, Mette L., Ranjitkar, Samir, Rajakaruna, Rupika S., Amerasinghe, Priyanie H., Morales, Francisco, Pearce, Richard, Ord, Rosalyn, Leslie, Toby, Rowland, Mark, Gadalla, Nahla B., Konradsen, Flemming, Bygbjerg, Ib C., Roper, Cally, Alifrangis, Michael
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634971/
https://ncbi.nlm.nih.gov/pubmed/26539821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004196
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