Multiple Origins of Mutations in the mdr1 Gene—A Putative Marker of Chloroquine Resistance in P. vivax

BACKGROUND: Chloroquine combined with primaquine has been the recommended antimalarial treatment of Plasmodium vivax malaria infections for six decades but the efficacy of this treatment regimen is threatened by chloroquine resistance (CQR). Single nucleotide polymorphisms (SNPs) in the multidrug re...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Schousboe, Mette L., Ranjitkar, Samir, Rajakaruna, Rupika S., Amerasinghe, Priyanie H., Morales, Francisco, Pearce, Richard, Ord, Rosalyn, Leslie, Toby, Rowland, Mark, Gadalla, Nahla B., Konradsen, Flemming, Bygbjerg, Ib C., Roper, Cally, Alifrangis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634971/
https://ncbi.nlm.nih.gov/pubmed/26539821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004196
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