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ATP binding drives substrate capture in an ECF transporter by a release and catch mechanism

ECF transporters are a family of active transporters for vitamins. They are composed of four subunits: a membrane-embedded substrate-binding subunit (EcfS), a transmembrane coupling subunit (EcfT), and two ATP-binding cassette ATPases (EcfA and EcfA′). We have investigated the mechanism of the ECF t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Struct Mol Biol
Prif Awduron: Karpowich, Nathan K., Song, Jin Mei, Cocco, Nicolette, Wang, Da-Neng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634891/
https://ncbi.nlm.nih.gov/pubmed/26052893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3040
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