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ATP Binding to the Motor Domain from an ABC Transporter Drives Formation of a Nucleotide Sandwich Dimer

It has been proposed that the reaction cycle of ATP binding cassette (ABC) transporters is driven by dimerization of their ABC motor domains upon binding ATP at their mutual interface. However, no such ATP sandwich complex has been observed for an ABC from an ABC transporter. In this paper, we repor...

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Detalhes bibliográficos
Main Authors: Smith, Paul C., Karpowich, Nathan, Millen, Linda, Moody, Jonathan E., Rosen, Jane, Thomas, Philip J., Hunt, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516284/
https://ncbi.nlm.nih.gov/pubmed/12150914
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