Adoptive transfer of activated marrow-infiltrating lymphocytes induces measurable antitumor immunity in the bone marrow in multiple myeloma

Successful adoptive T cell therapy (ACT) requires the ability to activate tumor-specific T cells with the ability to traffic to the tumor site and effectively kill their target as well as persist over time. We hypothesized that ACT using marrow-infiltrating lymphocytes (MILs) in multiple myeloma (MM...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Sci Transl Med
Päätekijät: Noonan, Kimberly A., Huff, Carol A., Davis, Janice, Lemas, M. Victor, Fiorino, Susan, Bitzan, Jeffrey, Ferguson, Anna, Emerling, Amy, Luznik, Leo, Matsui, William, Powell, Jonathan, Fuchs, Ephraim, Rosner, Gary L., Epstein, Caroline, Rudraraju, Lakshmi, Ambinder, Richard F., Jones, Richard J., Pardoll, Drew, Borrello, Ivan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634889/
https://ncbi.nlm.nih.gov/pubmed/25995224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa7014
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