Osteoprotegerin (OPG), The Endogenous Inhibitor of Receptor Activator of NF-κB Ligand (RANKL), is Dysregulated in BRCA Mutation Carriers

Breast cancer development in BRCA1/2 mutation carriers is a net consequence of cell-autonomous and cell nonautonomous factors which may serve as excellent targets for cancer prevention. In light of our previous data we sought to investigate the consequences of the BRCA-mutation carrier state on RANK...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Widschwendter, Martin, Burnell, Matthew, Fraser, Lindsay, Rosenthal, Adam N., Philpott, Sue, Reisel, Daniel, Dubeau, Louis, Cline, Mark, Pan, Yang, Yi, Ping-Cheng, Gareth Evans, D., Jacobs, Ian J., Menon, Usha, Wood, Charles E., Dougall, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634624/
https://ncbi.nlm.nih.gov/pubmed/26629528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.08.037
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