Dysregulation of the RANKL/RANK/OPG axis in thalassemia intermedia patients

Abstract Objective Thalassemia intermedia (TI) describes a disease ranging in severity between β thalassemia major (TM) and β thalassemia trait. Osteoporosis is observed in TI and TM. The exact reason of osteoporosis in TI could be hypogonadism and/or an increase in erythropoietin (EPO) levels. The...

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Hlavní autoři: Mahmoud A. Alfaqih, Nabil Bashir, Rami Saadeh, Yousef Khader, Musa Barqawi, Sara Alqudah
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2018-07-01
Edice:BMC Research Notes
Témata:
Thalassemia intermedia
Osteoporosis
Bone mineral density
Receptor activator of NF-kappaB ligand
Osteoprotegerin
On-line přístup:http://link.springer.com/article/10.1186/s13104-018-3616-y
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