Structure-based inhibitor design by using protein models for the development of antiparasitic agents.

The lack of an experimentally determined structure of a target protein frequently limits the application of structure-based drug design methods. In an effort to overcome this limitation, we have investigated the use of computer model-built structures for the identification of previously unknown inhi...

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Bibliografiske detaljer
Main Authors: Ring, C S, Sun, E, McKerrow, J H, Lee, G K, Rosenthal, P J, Kuntz, I D, Cohen, F E
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC46345/
https://ncbi.nlm.nih.gov/pubmed/8475107
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