Estimating Efficacy in a Randomized Trial With Product Nonadherence: Application of Multiple Methods to a Trial of Preexposure Prophylaxis for HIV Prevention

Antiretroviral preexposure prophylaxis (PrEP) for persons at high risk of human immunodeficiency virus infection is a promising new prevention strategy. Six randomized trials of oral PrEP were recently conducted and demonstrated efficacy estimates ranging from 75% to no effect, with nonadherence lik...

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Bibliografiska uppgifter
I publikationen:Am J Epidemiol
Huvudupphovsmän: Murnane, Pamela M., Brown, Elizabeth R., Donnell, Deborah, Coley, R. Yates, Mugo, Nelly, Mujugira, Andrew, Celum, Connie, Baeten, Jared M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Practice of Epidemiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634306/
https://ncbi.nlm.nih.gov/pubmed/26487343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwv202
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