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The Lin28/let-7 axis is critical for myelination in the peripheral nervous system

MicroRNAs (miRNAs) are crucial regulators of myelination in the peripheral nervous system (PNS). However, the miRNAs species involved and the underlying mechanisms are largely unknown. We found that let-7 miRNAs are highly abundant during PNS myelination and that their levels are inversely correlate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Gökbuget, Deniz, Pereira, Jorge A., Bachofner, Sven, Marchais, Antonin, Ciaudo, Constance, Stoffel, Markus, Schulte, Johannes H., Suter, Ueli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634210/
https://ncbi.nlm.nih.gov/pubmed/26466203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9584
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