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IRSp53 senses negative membrane curvature and phase separates along membrane tubules
BAR domain proteins contribute to membrane deformation in diverse cellular processes. The inverted-BAR (I-BAR) protein IRSp53, for instance, is found on the inner leaflet of the tubular membrane of filopodia; however its role in the formation of these structures is incompletely understood. Here we d...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Pub. Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4634128/ https://ncbi.nlm.nih.gov/pubmed/26469246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9529 |
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