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Reactivation of IgG-switched memory B cells by BCR-intrinsic signal amplification promotes IgG antibody production
Secondary antibody responses are marked by faster kinetics, improved antibody affinity and a switch from IgM to other immunoglobulin isotypes, most notably IgG, compared with primary responses. These changes protect from reinfection and represent the principle of most vaccination strategies. Yet, th...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nat Commun |
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| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Publishing Group
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4633962/ https://ncbi.nlm.nih.gov/pubmed/26815242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9575 |
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