Regulation of cardiac miR-208a, an inducer of obesity, by Rapamycin and Nebivolol

OBJECTIVE: Resistance to obesity is observed in rodents and humans treated with Rapamycin (Rap) or Nebivolol (Neb). Since cardiac miR-208a promotes obesity, we tested whether the modes of actions of Rap and Neb involve inhibition of miR-208a. METHODS: Mouse cardiomyocyte HL-1 cells and Zucker obese...

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Bibliografiske detaljer
Udgivet i:Obesity (Silver Spring)
Main Authors: Gul, Rukhsana, Mahmood, Abuzar, Luck, Christian, Lum-Naihe, Kelly, Alfadda, Assim A, Speth, Robert C., Pulakat, Lakshmi
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633375/
https://ncbi.nlm.nih.gov/pubmed/26381051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21227
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