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Progressive irreversible hearing loss is caused by stria vascularis degeneration in an Slc26a4-insufficient mouse model of large vestibular aqueduct syndrome

Hearing loss of patients with enlargement of the vestibular aqueduct (EVA) can fluctuate or progress, with overall downward progression. The most common detectable cause of EVA is mutations of SLC26A4. We previously described a transgenic Slc26a4-insufficient mouse model of EVA in which Slc26a4 expr...

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Publicat a:Neuroscience
Autors principals: Ito, Taku, Nishio, Ayako, Wangemann, Philine, Griffith, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633361/
https://ncbi.nlm.nih.gov/pubmed/26363152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2015.09.016
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