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Alterations in primary motor cortex neurotransmission and gene expression in hemi-Parkinsonian rats with drug-induced dyskinesia

Treatment of Parkinson’s disease (PD) with dopamine replacement relieves symptoms of poverty of movement, but often causes drug-induced dyskinesias. Accumulating clinical and pre-clinical evidence suggests that the primary motor cortex (M1) is involved in the pathophysiology of PD and that modulatin...

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Bibliografiske detaljer
Udgivet i:Neuroscience
Main Authors: Lindenbach, David, Conti, Melissa M., Ostock, Corinne Y., Dupre, Kristin B., Bishop, Christopher
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633339/
https://ncbi.nlm.nih.gov/pubmed/26363150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2015.09.018
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