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Demonstration of Therapeutic Equivalence of Fluconazole Generic Products in the Neutropenic Mouse Model of Disseminated Candidiasis

Some generics of antibacterials fail therapeutic equivalence despite being pharmaceutical equivalents of their innovators, but data are scarce with antifungals. We used the neutropenic mice model of disseminated candidiasis to challenge the therapeutic equivalence of three generic products of flucon...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gonzalez, Javier M., Rodriguez, Carlos A., Zuluaga, Andres F., Agudelo, Maria, Vesga, Omar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633286/
https://ncbi.nlm.nih.gov/pubmed/26536105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141872
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