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Demonstration of Therapeutic Equivalence of Fluconazole Generic Products in the Neutropenic Mouse Model of Disseminated Candidiasis

Some generics of antibacterials fail therapeutic equivalence despite being pharmaceutical equivalents of their innovators, but data are scarce with antifungals. We used the neutropenic mice model of disseminated candidiasis to challenge the therapeutic equivalence of three generic products of flucon...

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Pubblicato in:PLoS One
Autori principali: Gonzalez, Javier M., Rodriguez, Carlos A., Zuluaga, Andres F., Agudelo, Maria, Vesga, Omar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633286/
https://ncbi.nlm.nih.gov/pubmed/26536105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141872
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