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Prostate Cancer Heterogeneous High-Metastatic Multi-Organ-Colonizing Chemo-Resistant Variants Selected by Serial Metastatic Passage in Nude Mice Are Highly Enriched for Multinucleate Giant Cells

In order to further understand the role of tumor heterogeneity in metastasis and chemo-resistance, high metastatic PC-3 human prostate cancer variants were selected by injecting parental PC-3 cells, expressing green fluorescent protein (GFP) in the footpad of nude mice, which then metastasize to ing...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Zhang, Lei, Wu, Chengyu, Hoffman, Robert M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633180/
https://ncbi.nlm.nih.gov/pubmed/26536025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140721
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