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Prostate Cancer Heterogeneous High-Metastatic Multi-Organ-Colonizing Chemo-Resistant Variants Selected by Serial Metastatic Passage in Nude Mice Are Highly Enriched for Multinucleate Giant Cells
In order to further understand the role of tumor heterogeneity in metastasis and chemo-resistance, high metastatic PC-3 human prostate cancer variants were selected by injecting parental PC-3 cells, expressing green fluorescent protein (GFP) in the footpad of nude mice, which then metastasize to ing...
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出版年: | PLoS One |
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主要な著者: | , , |
フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4633180/ https://ncbi.nlm.nih.gov/pubmed/26536025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140721 |
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