Inhibitor of p52 NF-κB subunit and androgen receptor (AR) interaction reduces growth of human prostate cancer cells by abrogating nuclear translocation of p52 and phosphorylated AR(ser81)

Accumulating evidence shows that androgen receptor (AR) activation and signaling plays a key role in growth and progression in all stages of prostate cancer, even under low androgen levels or in the absence of androgen in the castration-resistant prostate cancer. Sustained activation of AR under and...

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Detalhes bibliográficos
Publicado no:Genes Cancer
Main Authors: Mehraein-Ghomi, Farideh, Church, Dawn R., Schreiber, Cynthia L., Weichmann, Ashley M., Basu, Hirak S., Wilding, George
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633170/
https://ncbi.nlm.nih.gov/pubmed/26622945
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