Generation of Novel Chimeric Mice with Humanized Livers by Using Hemizygous cDNA-uPA/SCID Mice

We have used homozygous albumin enhancer/promoter-driven urokinase-type plasminogen activator/severe combined immunodeficient (uPA/SCID) mice as hosts for chimeric mice with humanized livers. However, uPA/SCID mice show four disadvantages: the human hepatocytes (h-heps) replacement index in mouse li...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Tateno, Chise, Kawase, Yosuke, Tobita, Yoshimi, Hamamura, Satoko, Ohshita, Hiroki, Yokomichi, Hiroshi, Sanada, Harumi, Kakuni, Masakazu, Shiota, Akira, Kojima, Yuha, Ishida, Yuji, Shitara, Hiroshi, Wada, Naoko A., Tateishi, Hiromi, Sudoh, Masayuki, Nagatsuka, Shin-ichiro, Jishage, Kou-ichi, Kohara, Michinori
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633119/
https://ncbi.nlm.nih.gov/pubmed/26536627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142145
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia