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Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs

The SLC22 family includes organic anion transporters (OATs), organic cation transporters (OCTs) and organic carnitine and zwitterion transporters (OCTNs). These are often referred to as drug transporters even though they interact with many endogenous metabolites and signaling molecules (Nigam, S.K.,...

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Veröffentlicht in:PLoS One
Hauptverfasser: Zhu, Christopher, Nigam, Kabir B., Date, Rishabh C., Bush, Kevin T., Springer, Stevan A., Saier, Milton H., Wu, Wei, Nigam, Sanjay K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633038/
https://ncbi.nlm.nih.gov/pubmed/26536134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140569
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