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A Rationally Designed Mutant of Plasma Platelet-Activating Factor Acetylhydrolase Hydrolyzes the Organophosphorus Nerve Agent Soman()
Organophosphorus compounds (OPs) such as sarin and soman are some of the most toxic chemicals synthesized by man. They exert toxic effects by inactivating acetylcholinesterase (AChE) and bind secondary target protein. Organophosphorus compounds are hemi-substrates for enzymes of the serine hydrolase...
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| Pubblicato in: | Biochim Biophys Acta |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4632840/ https://ncbi.nlm.nih.gov/pubmed/26343853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2015.09.001 |
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