A Rationally Designed Mutant of Plasma Platelet-Activating Factor Acetylhydrolase Hydrolyzes the Organophosphorus Nerve Agent Soman()

Organophosphorus compounds (OPs) such as sarin and soman are some of the most toxic chemicals synthesized by man. They exert toxic effects by inactivating acetylcholinesterase (AChE) and bind secondary target protein. Organophosphorus compounds are hemi-substrates for enzymes of the serine hydrolase...

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Bibliografiset tiedot
Julkaisussa:Biochim Biophys Acta
Päätekijät: Kirby, Stephen D., Norris, Joseph, Sweeney, Richard, Bahnson, Brian J., Cerasoli, Douglas M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632840/
https://ncbi.nlm.nih.gov/pubmed/26343853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2015.09.001
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