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Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine

Shikonin is an anthraquinone derivative extracted from the root of lithospermum. Shikonin is traditionally used in the treatment of inflammatory and infectious diseases such as hepatitis. Shikonin also inhibits proliferation and induces apoptosis in various tumors. However, the effect of shikonin on...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Zhang, Feng-Ying, Hu, Yi, Que, Zhong-You, Wang, Ping, Liu, Yun-Hui, Wang, Zhen-Hua, Xue, Yi-Xue
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632727/
https://ncbi.nlm.nih.gov/pubmed/26473829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161023823
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