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Streamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step

Often when generating recombinant affinity reagents to a target, one singles out an individual binder, constructs a secondary library of variants, and affinity selects a tighter or more specific binder. To enhance the throughput of this general approach, we have developed a more integrated strategy...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Huang, Renhua, Gorman, Kevin T., Vinci, Chris R., Dobrovetsky, Elena, Gräslund, Susanne, Kay, Brian K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632715/
https://ncbi.nlm.nih.gov/pubmed/26437402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161023587
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