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Enzymatic modification of plasma low density lipoproteins in rabbits: a potential treatment for hypercholesterolemia.

Phospholipase A2 (EC 3.1.1.4) hydrolyzes certain phospholipids of low density lipoprotein (LDL). Plasma clearance of phospholipase A2-modified human LDL is up to 17 times faster than that of native human LDL in hypercholesterolemic rabbits. Modification of blood lipoproteins of hypercholesterolemic...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Labeque, R, Mullon, C J, Ferreira, J P, Lees, R S, Langer, R
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1993
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46323/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8475095/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.8.3476
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