Common clonal origin of central and resident memory T cells following skin immunization

Central memory T (T(CM)) cells in lymph nodes (LN) and resident memory T (T(RM)) cells in peripheral tissues play distinct roles in protective immunity(1-5). Both are generated after primary infections, but the clonal origin of T(RM) and T(CM) cells is unclear. To address this question, mice were im...

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Pubblicato in:Nat Med
Autori principali: Gaide, Olivier, Emerson, Ryan O., Jiang, Xiaodong, Gulati, Nicholas, Nizza, Suzanne, Desmarais, Cindy, Robins, Harlan, Krueger, James G., Clark, Rachael A., Kupper, Thomas S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632197/
https://ncbi.nlm.nih.gov/pubmed/25962122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3860
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