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Human Epidermal Langerhans Cells Maintain Immune Homeostasis in Skin by Activating Skin Resident Regulatory T Cells

Recent discoveries indicate that the skin of a normal individual contains 10-20 billion resident memory T cells ( which include various T helper, T cytotoxic, and T regulatory subsets, that are poised to respond to environmental antigens. Using only autologous human tissues, we report that both in v...

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Detalhes bibliográficos
Main Authors: Seneschal, Julien, Clark, Rachael A., Gehad, Ahmed, Baecher-Allan, Clare M., Kupper, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716276/
https://ncbi.nlm.nih.gov/pubmed/22560445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.03.018
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