Enhanced insulin sensitivity in skeletal muscle and liver by physiological overexpression of SIRT6()

OBJECTIVE: Available treatment for obesity and type 2 diabetes mellitus (T2DM) is suboptimal. Thus, identifying novel molecular target(s) exerting protective effects against these metabolic imbalances is of enormous medical significance. Sirt6 loss- and gain-of-function studies have generated confou...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Anderson, Jason G., Ramadori, Giorgio, Ioris, Rafael M., Galiè, Mirco, Berglund, Eric D., Coate, Katie C., Fujikawa, Teppei, Pucciarelli, Stefania, Moreschini, Benedetta, Amici, Augusto, Andreani, Cristina, Coppari, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632175/
https://ncbi.nlm.nih.gov/pubmed/26629408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.09.003
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