High specific selectivity and Membrane-Active Mechanism of the synthetic centrosymmetric α-helical peptides with Gly-Gly pairs

We used a template-assisted approach to develop synthetic antimicrobial peptides, which differ from naturally occurring antimicrobial peptides that can compromise host natural defenses. Previous researches have demonstrated that symmetrical distribution patterns of amino acids contribute to the anti...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Wang, Jiajun, Chou, Shuli, Xu, Lin, Zhu, Xin, Dong, Na, Shan, Anshan, Chen, Zhihui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632126/
https://ncbi.nlm.nih.gov/pubmed/26530005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15963
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