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Slit Binding via the Ig1 Domain Is Essential for Midline Repulsion by Drosophila Robo1 but Dispensable for Receptor Expression, Localization, and Regulation in Vivo

The midline repellant ligand Slit and its Roundabout (Robo) family receptors constitute the major midline repulsive pathway in bilaterians. Slit proteins produced at the midline of the central nervous system (CNS) signal through Robo receptors expressed on axons to prevent them from crossing the mid...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Brown, Haley E., Reichert, Marie C., Evans, Timothy A.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632062/
https://ncbi.nlm.nih.gov/pubmed/26362767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.022327
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