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Slit Binding via the Ig1 Domain Is Essential for Midline Repulsion by Drosophila Robo1 but Dispensable for Receptor Expression, Localization, and Regulation in Vivo

The midline repellant ligand Slit and its Roundabout (Robo) family receptors constitute the major midline repulsive pathway in bilaterians. Slit proteins produced at the midline of the central nervous system (CNS) signal through Robo receptors expressed on axons to prevent them from crossing the mid...

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Vydáno v:G3 (Bethesda)
Hlavní autoři: Brown, Haley E., Reichert, Marie C., Evans, Timothy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632062/
https://ncbi.nlm.nih.gov/pubmed/26362767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.022327
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