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Indoleamine 2,3-dioxygenase-dependent neurotoxic kynurenine metabolism mediates inflammation-induced deficit in recognition memory

Cognitive dysfunction in depression is a prevalent and debilitating symptom that is poorly treated by the currently available pharmacotherapies. Research over the past decade has provided evidence for proinflammatory involvement in the neurobiology of depressive disorders and symptoms associated wit...

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Publicat a:Brain Behav Immun
Autors principals: Heisler, Jillian M., O’Connor, Jason C.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631688/
https://ncbi.nlm.nih.gov/pubmed/26130057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2015.06.022
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