Intracellular Networks of the PI3K/AKT and MAPK Pathways for Regulating Toxoplasma gondii-Induced IL-23 and IL-12 Production in Human THP-1 Cells

Interleukin (IL)-23 and IL-12 are closely related in structure, and these cytokines regulate both innate and adaptive immunity. However, the precise signaling networks that regulate the production of each in Toxoplasma gondii-infected THP-1 monocytic cells, particularly the PI3K/AKT and MAPK signali...

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Опубликовано в: :PLoS One
Главные авторы: Quan, Juan-Hua, Chu, Jia-Qi, Kwon, Jaeyul, Choi, In-Wook, Ismail, Hassan Ahmed Hassan Ahmed, Zhou, Wei, Cha, Guang-Ho, Zhou, Yu, Yuk, Jae-Min, Jo, Eun-Kyeong, Lee, Young-Ha
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631599/
https://ncbi.nlm.nih.gov/pubmed/26528819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141550
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