Intracellular Networks of the PI3K/AKT and MAPK Pathways for Regulating Toxoplasma gondii-Induced IL-23 and IL-12 Production in Human THP-1 Cells

Interleukin (IL)-23 and IL-12 are closely related in structure, and these cytokines regulate both innate and adaptive immunity. However, the precise signaling networks that regulate the production of each in Toxoplasma gondii-infected THP-1 monocytic cells, particularly the PI3K/AKT and MAPK signali...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Quan, Juan-Hua, Chu, Jia-Qi, Kwon, Jaeyul, Choi, In-Wook, Ismail, Hassan Ahmed Hassan Ahmed, Zhou, Wei, Cha, Guang-Ho, Zhou, Yu, Yuk, Jae-Min, Jo, Eun-Kyeong, Lee, Young-Ha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631599/
https://ncbi.nlm.nih.gov/pubmed/26528819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141550
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